Apoptosis — Intrinsic/Extrinsic Machinery and Triggers
3 pointsPyroptosis caspase-1 vs apoptotic caspase-type discrimination
Apoptosome cytochrome-c/APAF-1 and intrinsic-pathway localization
Fas/CD95 death-receptor inducers vs anti-apoptotic Bcl-2
Every topic broken into what's actually asked from it. Tick what you've already studied — mark it Shaky if you'd fumble it under exam pressure.
Pyroptosis caspase-1 vs apoptotic caspase-type discrimination
Apoptosome cytochrome-c/APAF-1 and intrinsic-pathway localization
Fas/CD95 death-receptor inducers vs anti-apoptotic Bcl-2
Hemophilia carrier/offspring risk and prenatal diagnosis from pedigree
X-linked dominant vs recessive disorder identification
Inheritance-mode to disorder matching
Metaplasia-dysplasia-anaplasia grading and reversible pleomorphism
Cancers not spreading lymphatically (BCC and others)
Germline retinoblastoma second cancers and intraocular metastasis
Disruption vs malformation developmental error
ADA-SCID absent tonsils and NHEJ repair defect
CD40/CD40L defect and hyper-IgM isotype-switch failure
Eczema-thrombocytopenia-infection Wiskott-Aldrich triad
Birbeck granules and CD1a/S100/Langerin markers
Kikuchi necrotizing lymphadenitis recognition
B12 subacute combined degeneration and paresthesia vignette
Macrocytic smear, hypersegmented neutrophils and hyperpigmentation
Megaloblastic feature 'not present/least likely' exclusion
Hereditary spherocytosis membrane defect and splenomegaly
G6PD RBC changes and sickle heterozygote malaria protection
Direct/indirect Coombs and IgM-mediated immune hemolysis
Aplastic marrow failure, benzene and hypoplastic-marrow anemia
Pancytopenia cause identification on blood counts
Myelofibrosis dry-tap marrow aspiration
Normal-marrow fatigue anemia workup
HCM athlete sudden-death autopsy findings
Lymphocytic myocarditis and restrictive/amyloid heart failure
WPW delta-wave pre-excitation management
Takayasu pulseless and Kawasaki strawberry-tongue features
C-ANCA GPA and small-vessel vasculitis identification
Granulomatous-vasculitis association exception
Squamous carcinoma keratin pearls and P40 marker
Squamous carcinoma clinical picture and hilar anthracotic pigment
Small-cell and carcinoid neuroendocrine identification
Central mass, paraneoplastic hypercalcemia and lung-carcinoma statement trap
COVID diffuse-alveolar-damage autopsy and EM findings
ARDS/shock-lung cause and bilateral-infiltrate picture
Indirect ARDS injury and smoke-inhalation death mechanism
Trauma-associated ARDS after multiple fractures
Croup causative organism and atypical-pneumonia statement
Lobar pneumonia, cavitary lesions and TB pleural effusion
Fungal middle-lobe lesion and nasal-polyp rhinosinusitis
Respiratory image and graph interpretation
Hamartomatous juvenile and Peutz-Jeghers polyps
FAP/APC-mutation exception and pseudopolyps
Colon-cancer genetic-change identification
Hirschsprung aganglionosis commonest site and absent ganglia
Gastric ulcer site, epithelial tumor and H. pylori variability
Oral tongue carcinoma papillae involvement
Wilson choreoathetoid KF-ring and CMV owl-eye inclusion
Meckel diverticulum commonest ectopic tissue
Reye cerebral edema and acute pancreatitis etiology
Acute-abdomen perforation X-ray and splenic-abscess imaging
Minimal-change foot-process effacement and GBM statements
Childhood nephrotic clinical presentation and urinalysis
Nephrotic hypercoagulability and steroid-resistant NPHS gene
PAN and malignant-hypertension onion-peel fibrinoid necrosis
Bartter-syndrome tubular transporter defect
Acute kidney injury marker exclusion
Seminoma and yolk-sac germ-cell tumor markers
Leydig Reinke-crystal, Sertoli-only azoospermia and hypogonadism
Prostate carcinoma high acid-phosphatase
Ovarian tumor matching and histology identification
Dysgerminoma LDH and ovarian clear-cell location
Granulosa-cell tumor inhibin biomarker
Papillary carcinoma Orphan-Annie nuclei and BRAF/RET mutation
Papillary strap-muscle invasion and lymphatic spread
Medullary carcinoma amyloid, C-cell origin and neuroendocrine granules
Adrenal incidentaloma commonest cause
Acromegaly prognathism GNAS/Gsp mutation
Mediastinal mass thymoma vs ALL distinction
Pleomorphic adenoma feature exclusion
Endocrine histopathology image matching
Ewing diaphyseal lesion with onion-skin periosteal reaction
Proptosis small round-cell desmin/MIC2 immunophenotype
EWSR1-FLI1 mutation and confirmatory test
Metaphyseal osteosarcoma and fibroblastic lytic lesion
Prosthesis-loosening metallosis and LCH skull/bone lesion
Marfan fibrillin mutation and myxoid liposarcoma t(12;16)
Gout/pseudogout crystal arthropathy identification
Reactive arthritis keratoderma blennorrhagica
Alzheimer amyloid-beta/tau protein and neuritic inclusions
Alzheimer type-II astrocytes and senile atrophy statements
Verocay bodies and Antoni A/B schwannoma morphology
Proptosis and wrist nerve-sheath tumor identification
Craniopharyngioma machinery-oil and rosette-forming tumors
Neuronal-tumor exception and glioma-inducing receptor
86 more Pathology topics inside RankPG
Free forever plan · no credit card · 30-second signup