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Biochemistry revision checklist for NEET PG, INI-CET & FMGE

Every topic broken into what's actually asked from it. Tick what you've already studied — mark it Shaky if you'd fumble it under exam pressure.

General Biochemistry

Enzyme Kinetics and Graphical Analysis

5 points

Reading double-reciprocal inhibitor patterns from the plot

BOTH🖼 Image2016, 2022, 2024

Zero-order behaviour when substrate is far above Km

INI🖼 Image2018, 2020

Cooperative sigmoid enzymes and bisubstrate ping-pong

NEET2019

Saturable carrier versus linear diffusion transport curve

INI🖼 Image2016, 2021

Ranking enzymes by kcat over Km

INI2020

Collagen and Fibrous Proteins

3 points

Vitamin C, prolyl/lysyl hydroxylation and scurvy

INI2013, 2021, 2023

Matching collagen types to tissues and building blocks

INI2014, 2015, 2018 +1

Elastin defects and keratin disulfide cross-linking

BOTH2016, 2018

Heme Synthesis and Porphyrias

3 points

Lead-sensitive heme enzymes and what accumulates

INI2015

Acute porphyria presentation and attack triggers

BOTH2017, 2024

Heme pathway enzymes, sites and the mature RBC exception

BOTH2015, 2019, 2024 +1

Mitochondrial ETC and Inhibitors

3 points

Naming the terminal complex that cyanide and CO poison

BOTH2022, 2024, 2025 +1

Separating an ATP synthase blocker from an uncoupler

BOTH2016, 2019, 2021 +1

Spotting the cytosolic pathway among mitochondrial ones

NEET2015, 2016

Carbohydrate Metabolism

Glycogen Storage Disorders

4 points

Floppy infant with cardiomegaly on the chest film

BOTH🖼 Image2023, 2024

Adolescent exercise cramps with flat lactate

BOTH2018, 2022, 2023

Fasting hypoglycemia that ignores glucagon

BOTH2013, 2015

Glucagon works after a meal but not after a fast

BOTH2016, 2023, 2025

Glycogen Metabolism Enzymes

4 points

What switches glycogen phosphorylase on in muscle

INI2022, 2023

The vitamin cofactor unique to phosphorylase

INI2015, 2017

The enzyme common to synthesis and breakdown

INI2014, 2015

Why glucose is stored as branched glycogen

BOTH2012, 2019, 2020

Gluconeogenesis

3 points

The substrate that cannot make net glucose

INI2015, 2016, 2021

Unique gluconeogenic enzymes versus shared steps

INI2020

What drives gluconeogenesis in prolonged fasting

BOTH2012, 2016, 2019 +1

Fasting and Starvation Adaptation

3 points

Source of glucose after an overnight fast

BOTH2016, 2018, 2021

Which change does NOT occur in prolonged fasting

NEET2016

The obligate glucose users during fasting

INI2014, 2015, 2021

Lipid Metabolism

Lipoprotein Metabolism and Transport

4 points

Which component dominates HDL and its migration

BOTH2015, 2016

ABCA1 mutation image pointing to a named disease

INI🖼 Image2022

Computing LDL from the Friedewald equation

INI2015

Highest cholesterol-containing food among choices

INI2012

Ketone Bodies and Ketoacidosis

3 points

Why the liver cannot use the ketones it makes

INI2013, 2023

Mechanism driving ketosis in type 1 diabetes

INI🖼 Image2020, 2023

Nitroprusside urine test that turns positive in ketosis

BOTH🖼 Image2015, 2017

Sphingolipidoses

2 points

Crumpled tissue paper cells and the deficient enzyme

BOTH🖼 Image2021, 2022, 2024 +2

Matching sphingomyelinase deficiency to its disease

NEET2015

Amino Acid Metabolism

Urea Cycle Disorders

4 points

Rate-limiting enzyme and the aspartate nitrogen link

NEET2014, 2019

How the brain detoxifies ammonia

INI2020

How phenylbutyrate lowers ammonia and its amino acid source

INI2017, 2024

Arginine handling in OTC deficiency and gyrate atrophy

BOTH2012, 2023

Amino Acid Chemistry and Ionization

3 points

Net side-chain charge and charge-neutral substitutions

INI2016, 2019

Polar residues on the surface, hydrophobic buried

NEET2017, 2018

Histidine imidazole as the protein buffering residue

NEET2014

Protein Precipitation and Folding

3 points

Heat precipitation that redissolves points to Bence Jones protein

NEET2016

Spotting the method that does not precipitate protein

INI2015, 2016

Chaperones fold nascent proteins in the ER

NEET2014, 2018

Vitamins and Minerals

Thiamine B1 Deficiency

2 points

Which dehydrogenase stalls when TPP is missing

INI2015, 2017, 2021

Separating Korsakoff memory loss from the Wernicke triad

BOTH2014, 2021

Niacin B3 and Pellagra

2 points

Maize-diet triad pointing to the deficient vitamin

NEET🖼 Image2021, 2023, 2024 +1

High-dose vitamin causing cystoid macular edema

NEET2020

Vitamin B12 and Folate

3 points

The only two human B12-dependent enzymes

INI2015, 2018, 2020

Why folate must not be given alone in suspected B12 lack

INI2021, 2022, 2024

Dietary source and localising the absorption block

BOTH2018, 2020

Vitamin C and Scurvy

2 points

Bleeding gums and poor healing from a hydroxylation block

NEET🖼 Image2019, 2023

Enzyme humans lack for vitamin C and its iron role

INI2018

Genetics

Molecular Diagnostics

3 points

Role of ddNTPs in Sanger sequencing

INI2022

RFLP strain typing and detecting DNA sequence changes

INI2017, 2023, 2025

Choosing the method for expression profiling versus viral load

BOTH2015, 2020

Cytogenetics Karyotyping and FISH

3 points

Ordering the karyotype culture and banding steps

BOTH2019, 2022, 2023 +1

Choosing FISH versus PCR for locus and aneuploidy detection

BOTH🖼 Image2014, 2021, 2024 +2

Spotting the non-aneuploidy and the abnormal-division product

INI2011, 2013, 2025

Epigenetics and Methylation

4 points

What DNA methylation does and does not participate in

INI2014, 2020

The cytosine change that closes permissive chromatin

INI2016, 2018

Parent-of-origin differential expression and how to detect it

INI2014, 2015, 2022

The named principle behind X-chromosome inactivation

NEET2014

Purine Pyrimidine Metabolism and Gout

3 points

Lesch-Nyhan clinical clue, enzyme and inheritance

NEET2016, 2017, 2018

Primary gout urate handling and acute-attack findings

NEET2015, 2021, 2023

Spotting the pyrimidine disorder among purine diseases

NEET2014, 2019

65 more Biochemistry topics inside RankPG

Tick off what you've already studied.